an Endocrine Society Thematic Issue
Read our special collection of journal articles focused on men’s health research! Curation of the collection, based on articles published in 2020 to 2022, was guided by Altmetric Attention Scores and Featured Article designations.
In Journal of the Endocrine Society, Vogiatzy and coauthors discuss testosterone use in adolescent males, concluding that a lack of long-term safety data and suitable formulations limit its use. Varimo et al. report that liver-enriched antimicrobial peptide 2 levels decrease after induction of puberty in boys, reciprocally with increased growth rate and energy demand. And Fujisawa and colleagues report that intrauterine hyponutrition reduces postnatal sperm count in mice.
Writing in Endocrinology, Schjenken and associates report that in the mouse, an obesogenic, high-fat diet alters the composition of seminal plasma in a way that limits its ability to induce a tolerogenic immune response in females at conception. Houston and colleagues describe how variants of the human inhibin gene that cause infertility in men alter testis composition but do not affect fertility when transferred into mice. Kim et al. report that testosterone reduces body fat via two separate receptors and two mechanisms in male mice, one of them including increased physical activity.
In JCEM, Woodward and coauthors report on associations between serum sex hormone levels and urinary phthalate metabolite concentrations in men, finding no overall link but some age-specific associations. Windfeld-Mathiasen et al. discover that males using androgens have temporarily lowered fertility. Liu et al. find significant associations between serum osteocalcin and metabolic syndrome in men over 70, with the carboxylation state of the hormone being critical.
Endocrine Reviews has an in-depth review by Mason and coauthors of the role of androgens in male maturation and development. Zhu and associates survey the changing face of adrenoleukodystrophy, an X-linked condition that can cause adrenal insufficiency and is increasingly being detected in newborn screening. Handelsman assesses androgen misuse and abuse, a problem that greatly exceeds its medically validated uses.
Published: April 2022
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, and The Journal of Clinical Endocrinology & Metabolism, so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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