an Endocrine Society Thematic Issue
Read our special collection of journal articles, published in 2020–2022, focused on the microbiome! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designations.
Jensen and colleagues, in Journal of the Endocrine Society, find in a longitudinal evaluation study a significant direct effect of cesarean delivery on the glycemic status of adults, an effect hypothesized to result from alterations in the gut microbiome in early life. Rizk and Thackray provide a review of studies linking the microbiome to polycystic ovary syndrome (PCOS), concluding that “dysbiosis of the gut microbiome may be sufficient” to cause the development of PCOS-like symptoms. Heath et al. find in a scoping review persistent alterations in the levels of metabolites associated with the gut microbiome in pregnant women who develop gestational diabetes mellitus.
In JCEM, Hong and coauthors report multiple changes, including changes in the gut microbiota, in obese patients treated with vertical sleeve gastrectomy. Lüll et al. report that women of late fertile age with and without PCOS did not have different gut microbial profiles, although those with prediabetes and PCOS had lower alpha diversity of the gut microbiome. Wei and coauthors report on an association between heart failure with preserved ejection fraction and trimethyllysine, an association influenced by trimethylamine-N-oxide, a derivative of microbial metabolism.
In Endocrinology, Massey and Brown review the “gut microbial endocrine organ” as it relates to type 2 diabetes. Jensen and associates report that in mice, expression of bovine growth hormone alters the gut microbiome in an age-dependent manner. Alvarez et al. review the microbiome as a circadian coordinator of metabolism, considering its diurnal aspects.
In Endocrine Reviews, Yang and colleagues assess the state of knowledge on uterine fibroids, which seem to be influence by the microbiome of the reproductive tract. Angelidi et al. consider the gut microbiome, among other targets, in the context of novel approaches to the treatment of obesity. And Olofsson and Bäckhed discuss how the gut microbiome contributes to cardiometabolic disease generally--and how gut bacteria can be targeted in treatments.
Published: October 2022
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, and The Journal of Clinical Endocrinology & Metabolism, so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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