an Endocrine Society Thematic Issue
Read our special collection of journal articles, published in 2019–2020, focused on neuroendocrinology! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designations.
In Endocrine Reviews, Hofland and his coauthors discuss advances in the diagnosis and management of neuroendocrine neoplasms, which despite their heterogeneity share features of neural differentiation. Vegeto and colleagues discuss the potential role of sex steroids and their receptors in major neurodegenerative diseases, including Alzheimer disease. Yamamoto and coauthors discuss the newly identified anti-PIT-1 hypophysitis and its connection to isolated ACTH deficiency.
In Endocrinology, Arambula and McCarthy discuss how sex-specific brain development is a result not just of sex hormones, but also of crosstalk between the neuroendocrine and immune systems. Cox and coauthors describe experiments with a mouse model showing that androgen action in the brain and in adipose tissue is key in the development of polycystic ovary syndrome. Deol and colleagues, in an article that got a remarkable amount of online attention, report that soybean oil diets in male mice upregulated transcription of hypothalamic genes associated with inflammation and signaling, and were associated with glucose intolerance.
In JCEM, Miller and co-investigators report on the effects of clomiphene on the hypothalamic-pituitary-testicular axis in recreationally active males. Strong elevations of testosterone and gonadotropins were found to persist for months even after one month of exposure, suggesting the possibility of the drug being abused by athletes. Pofi and coauthors examined recovery of the hypothalamo-pituitary-adrenal axis after transsphenoidal adenectomy: Recovery can occur as long as a year after surgery. Cristante and colleagues compared adenectomy patients who have a typically visualized adenoma by MRI with those who have an inconclusive or normal MRI, and argue for the superiority of a surgeon’s judgment, with endoscopy, over MRI imaging.
Journal of the Endocrine Society has an article by Suarez and colleagues that describes their studies of the prevalence of thrombotic events in patients with Cushing syndrome, including some with Cushing disease. Kleindienst and colleagues report on the effectiveness of tolvaptan compared with fluid restriction at preventing hyponatremia resulting from syndrome of inappropriate antidiuretic hormone secretion after pituitary surgery. Fagundes and coauthors report that pheochromocytoma is strongly associated with missense mutations in the VHL gene of young patients with Von Hippel-Lindau syndrome.
Published: August 2020
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, and The Journal of Clinical Endocrinology & Metabolism, so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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