Endocrine Society Thematic Issue
Read our special collection of journal articles, published in 2019–2021, focused on obesity! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designations.
In Endocrine Reviews, Blüher discusses the concept of metabolically healthy obesity, describing it as a “transient phenotype.” Lega and Lipscombe analyze the complex relationship between obesity, diabetes, and cancer, focusing on epidemiological and pathophysiological evidence. Yabut and colleagues examine the role of serotonin in the regulation of metabolism: Inhibiting synthesis of the neurotransmitter could offer a way to treat obesity.
Endocrinology features Schlaepfer and Joshi describing fatty oxidation mediated by CPT1A, the liver isoform of the enzyme involved in the rate-limiting step of fatty acid oxidation, which could also be a target for pharmacotherapy of obesity. Egusquiza and Blumberg review new evidence about the effects and mechanisms of environmental obesogens, and Das and coauthors evaluate information about the role of mitochondrial dysfunction in obesity and other conditions.
In JCEM, Johansen and colleagues report that overweight and obese children and adolescents have elevated biochemical markers of liver damage. Shen and coauthors report a surprising inverse association between body mass index and stroke risk in patients with type 2 diabetes. Lin and colleagues report finding gut bacteria dysbiosis in patients with “normal weight obesity” — normal body mass index but elevated fat as a fraction of body composition.
Journal of the Endocrine Society has Thomas et al. reviewing the role of hyperinsulinemia in obesity and other metabolic dysfunction, with a focus on racial and ethnic differences and its role as an early indicator. Shimy and colleagues describe metabolic ward results that support the carbohydrate-insulin model of obesity. And Ruiz and co-authors discuss the possible importance of glucocorticoid-sex steroid crosstalk in metabolic derangements, including obesity.
Published: January 2021
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, and The Journal of Clinical Endocrinology & Metabolism, so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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