an Endocrine Society Thematic Issue
Read our special collection of journal articles, published in 2022–2023, focused on pediatric endocrinology! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designations.
In Journal of the Endocrine Society, Dubose and colleagues report on normative sensory data and glycemic measures in healthy children without diabetes. McGlacken-Byrne and coauthors discuss management of three girls with delayed puberty and hypergonadotropic amenorrhea of different etiologies. Calvert et al. find that disrupting the slow-wave sleep of pubertal children with sound had no effect on growth hormone pulse amplitude or basal growth hormone secretion.
In JCEM Case Reports, Nasomyont and associates describe the successful treatment of hypoglycemia with alpelisib in pediatric patients with PIK3CA-related overgrowth spectrum. Vitale and Laffel describe the successful use of insulin in a child with new-onset type 1 diabetes accompanied by diabetic ketoacidosis and severe hypertriglyceridemia. Shimura and colleagues report on two Japanese infants who developed hypothyroidism requiring levothyroxine treatment after exposure to iodinated contrast media.
In Endocrine Reviews, Federici et al. review in depth the therapeutic options for inducing puberty in patients with hypogonadism and highlight “persistent shortcomings in clinical practice.” Brito and coauthors discuss the disparate congenital and acquired mechanisms implicated in the etiology of central precocious puberty. Hokken-Koelega and coauthors describe an international consensus guideline on treatment of infants and older children small for gestational age, including discussion of newly identified genetic and epigenetic causes.
In Endocrinology, Guo and co-workers describe research providing insights into the role of casein kinase 1α in testicular development and steroidogenesis. Lin et al. describe second generation programming of the hypothalamic — pituitary — adrenal axis of male rat offspring by a maternal high-fat diet. Evans and associates identify a crucial role for leptin in controlling the onset of female puberty in pituitary adenylate cyclase-activating polypeptide-expressing neurons.
In JCEM, Haj-Ahmad and colleagues document how the serum insulin-like growth factor-1/insulin-like growth factor binding protein-3 ratio can be a useful marker for the diagnosis of growth hormone deficiency in children. Magnotto et al. describe novel mutations in the gene MKRN3 that were identified in a cohort of children with central precocious puberty and that affect ubiquitination in different ways. And Jee and coauthors summarize recent findings on the associations between early infantile growth, the timing of puberty, and metabolic risks.
Published: August 2023
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, The Journal of Clinical Endocrinology & Metabolism, and JCEM Case Reports so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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